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Wednesday, December 11, 2019

Ipratropium Bromide Is An Bronchodilator †Myassignmenthelp.Com

Question: Discuss About The Ipratropium Bromide Is An Bronchodilator? Answer: Introducation Ipratropium bromide is an antimuscarinic bronchodilator. However, injection of this medicine increases the heart rate3. The medicine blocks the muscarinic receptors thus acetylcholine will decrease. When the level of acetylcholine decreases, the action of pacemaker increases by decreasing potassium and increasing economics of sodium and calcium hence increasing heart rate4. Neostigmine can reverse the non-depolarizing effects of vecuronium because vecuronium is not a deep neuromuscular block. Neostigmine competitively blocks the binding of vacuronium to its binding site2. In other cases, neostigmine may directly block the activities of vecuronium. By doing so, the effects of vecuronium are therefore reversed. Neostigmine can enhance the effects of decamethonium. Neostigmine enhances the effects of decamethonium as it raises the concentration of acetylcholine at the myoneural junction hence inability to stimulate muscle fiber, hence enhancing effects of decamethonium. The crop duster inhaled the organophosphates which inhibited cholinesterase enzyme in the body that is found in the nervous system whose function is to breakdown acetylcholine1. Upon the inactivation of cholinesterase, there is increase of acetylcholine in the nerves thus becoming overactive hence unable to breathe leading to death1. References Bentham Science Publisher, BenthamS. "Organophosphate Toxicity Relating to Exposure Route and Type of Agent."Chemical-Induced Seizures: management,Consequences and Treatment,2012, pp.39-48. Sasaki, Nobuo, et al. "Effects of Neostigmine Reversal of Nondepolarizing Neuromuscular Blocking Agents on Postoperative Respiratory Outcomes."Survey of Anesthesiology, vol.59, no.2,2015, pp.90-91. Singh, Sonal, et al. "Pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications." financial, vol.68, no.1,2012, pp.114-116. Singh, Sonal. "Republished: Pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications."Postgraduate Medical Journal, vol.90, no.1062,2014, pp.205-207.

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